Native Fluorescent Natural Deep Eutectic Solvents for Green Sensing Applications: Curcuminoids in <i>Curcuma longa</i> Powder

Natural deep eutectic solvents are a trending topic in Green Chemistry. These present high solubilization capacity, reusability, tunable properties, simple preparation, biodegradability, safety, availability, and low cost, making them excellent candidates for analytical applications. In this work, new family of fluorescent systems is described, with the fluorescence property being unknown unused so far. For purpose, novel preparation method using an ultrasound probe was employed, by means innovative single-step procedure, that included FCH (fructose, citric acid, water, 1:1:5 molar ratio) extraction/determination curcuminoids from Curcuma longa powder. This methodology successfully carried out employing portable inexpensive 3D-printed fluorometer smartphone. way, extraction efficiencies between 90 106%, relative to NIST reference method, were obtained just 3.40 min. Besides, greenness evaluated AGREE metric, showing developed approach >2.5 times greener than previously published works curcuminoid determination. groundbreaking procedure robust, versatile, implement, does not require sophisticated apparatus or instruments detection step, and, mainly, agrees Analytical Chemistry (GAC) principles.